3-Amino-2-fluoro-2,3,6-trideoxy-L-galactose 10 (α-fluoro-L daunosamine) was synthesized in ten steps starting from methyl-2, 3-anhydro-4,6-0-benzylidene-α-D-mannopyranoside (overall yield 70%). Et3N, 3HF complex was used as the fluorinating agent, according to our previous work, for replacement of a mesyl groun. Neighbouring-group participation lead to a fluorinated product with retention of configuration. The structure of10was determined by1H and19F NMR spectroscopy.