Experimental Homocystinemia, Endothelial Lesions and Thrombosis
作者:
Josef Hladovec,
期刊:
Journal of Vascular Research
(Karger Available online 1979)
卷期:
Volume 16,
issue 4
页码: 202-205
ISSN:1018-1172
年代: 1979
DOI:10.1159/000158207
出版商: S. Karger AG
关键词: Experimental homocystinemia;Endothelial lesions
数据来源: Karger
摘要:
A single intravenous injection of homocystine led to an increase in the number of circulating endothelial cells in the blood of rats. We observed also increased permeability of the lung capillaries, platelet sequestration and activation of the venostatic thrombosis. Endothelial injury is probably the key mechanism of thrombotic and atherosclerotic complications in homocystinuria, an inborn error of the amino acid metabolism.
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