Two new species of Caddisflies from the Great Basin region in California and Nevada are described. Lepidostoma castalianum sp. nov., collected at a spring in the White Mts. of Mono Co., California, is closely related to L. verodum Ross. L. ojanum sp. nov., collected at three separate springs in the White Mts. of Inyo Co., California, and one spring in Mineral Co., Nevada, is a member of the unicolor species group, similar to L. frosti (Milne) and L. unicolor (Banks).