Depth perception of 25 male college subjects was measured with the Howard-Dolman Apparatus and with various lenses from ± 2.00 D placed over one eye to induce anisometropia. Results showed that depth perceptual measures are very reliable (r = + 0.96) and that the average depth perceptual error is affected by both plus- as well as minus-lens induced antsometropia in the form of a V-shape curve, which is minimal at the vertex where there is zero lens addition over best visual acuity corrections, proportionally increases with both plus- and minus-lens induced anisometropia. and gradually levels off beyond the ± 1.00 D levels.