B Cell Chronic Lymphocytic Leukemia with Florid Reactive CD4 + T Cell Lymphocytosis in Lymph Nodes
作者:
BusmanisInny,
HusseinSonay,
FeleppaFrank,
RockmanSteven,
BegleyC. Glenn,
期刊:
Leukemia&Lymphoma
(Taylor Available online 1993)
卷期:
Volume 9,
issue 1-2
页码: 153-156
ISSN:1042-8194
年代: 1993
DOI:10.3109/10428199309148519
出版商: Taylor&Francis
关键词: Chronic lymphocytic leukemia;immunoglobulin/T cell receptor gene;re-arrangement;lymphocytosis
数据来源: Taylor
摘要:
This case is of an unusual florid reactive CD4 + T Cell lymphocytosis involving lymph node (LN) and overshadowing residual B chronic lymphocytic leukemia (CLL). A 65 year old female with a 9 year history of untreated B-CLL presented with weight loss, splenomegaly and lymphadenopathy. B-CLL was confirmed on the basis of peripheral Blood lymphocytosis, bone marrow trephine findings and flow cytometry analysis. However, the LN biopsy showed appearances of a diffuse small lymphocytic population mimicking a leukemic T-cell infiltrate. Immunophenotyping and molecular analysis demonstrated the major cell population to be reactive CD4 positive T lymphocytes.
点击下载:
PDF (803KB)
返 回