Orientation of Nuclei as Indicators of Smooth Muscle Cell Alignment in the Cerebral Artery
作者:
James G. Walmsley,
Peter B. Canham,
期刊:
Journal of Vascular Research
(Karger Available online 1979)
卷期:
Volume 16,
issue 1
页码: 43-51
ISSN:1018-1172
年代: 1979
DOI:10.1159/000158189
出版商: S. Karger AG
关键词: Smooth muscle;Stereology;Light microscopy;Brain arteries
数据来源: Karger
摘要:
Geometric measurements were made of the nuclei of the muscle cells of the tunica media of human intracranial arteries. The nuclei measured 37 ± (SD) 6.4 µm in length, and 2.0 ± (SD) 0.83 µm average width and have a number density of 105 nuclei/mm3 (number per unit volume of tunica media). From the work of others it was known that the nuclei are centrally located within the cytoplasm of the muscle cell; because of this we have used the nuclei as indicators of alignment of the muscle cells themselves, making measurements from light micrographs of arterial sections stained with haematoxylin and eosin. On average, the nuclei were oriented at an angle that was not significantly different from a zero-degree pitch for the five sections analyzed in det
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