Artificial caries-like lesions of enamel were subjected to each of the following treatments: storage in deionized water, fluoride application, heating and exposure to a calcifying fluid, and then reexposure to an artificial caries system. After reexposure, the lesions were examined by microradiography and polarizing microscopy. Mineralization of the periphery of the initial lesion was increased before these treatments. At this peripheral zone, a relatively well-mineralized lamination occurred. The development of laminations at the periphery of the initial lesions seems to be related to noncontinuous remineralization.