SummaryThree cases of renal-cell carcinoma with secondary amyloidosis are presented. A nephrotic syndrome was common to the three cases. In the first case a syndrome of malabsorption dominated the clinical picture. In the second case anemia was prominent. In the third case the nephrotic syndrome was severe; resection of the tumor did not improve the nephrotic syndrome which progressed to renal failure. The patient still survives the operation since three years.The symptomes of amyloidosis, more especially of gastro-intestinal amyloidosis are reviewed. The relationship between carcinomatosis and secondary amyloidosis are examined. The authors stress the fact that the association of renal-cell carcinoma and amyloidosis is not as rare as generally believed.