Calculation of recurrence risk in the case of ankylosing spondylitis taking into consideration the antigen HLA‐B‐27
作者:
B. Gömör,
I. Ratkó,
期刊:
Annals of Human Genetics
(WILEY Available online 1984)
卷期:
Volume 48,
issue 1
页码: 79-86
ISSN:0003-4800
年代: 1984
DOI:10.1111/j.1469-1809.1984.tb00837.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryThe authors have provided a new recurrence risk table of ankylosing spondylitis. The mathematical problem solved was to combine a continuous distribution for polygenic inheritance with a discrete one, HLA‐B‐27 antigen ‘yes’ or ‘no’. Previously the highest probability of recurrence was 0.0785 in the case of an affected mother's son and it increased to 0.1416 when the B‐27 antigen positive affected mother had a B‐
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