How Antenatal Ultrasound Diagnosis of Congenital Malformations Has Contributed to Fetal Outcome: A 22-Year Review
作者:
Eiichi Hori,
Takashi Koyanagi,
Toshiyuki Yoshizato,
Hirotaka Maeda,
Shoji Satoh,
Sachiyo Suita,
Kohji Ueda,
Hitoo Nakano,
期刊:
Fetal Diagnosis and Therapy
(Karger Available online 1993)
卷期:
Volume 8,
issue 6
页码: 388-401
ISSN:1015-3837
年代: 1993
DOI:10.1159/000263857
出版商: S. Karger AG
关键词: Congenital malformations;Antenatal diagnosis;Outcome;Human fetus;Ultrasonography
数据来源: Karger
摘要:
We herein reviewed 630 malformed fetuses delivered from 24 weeks of gestation onwards in our institute over the past 22 years. These fetuses were divided into 2 groups: 210 from 1970 to 1982 (group 1) and 420 from 1983 to 1991 (group 2). Twenty-two varieties of congenital malformations were diagnosed antenatally in group 1, whereas 55 additional malformations became diagnosable in group 2. Thirty-four varieties of congenital malformations still remained undiagnosed throughout the 22-year study period. Cases receiving ‘fetal therapy’ and ‘close obstetric care’ increased, with statistical significance, from 1.8 to 15.7%, and from 22.9 to 55.7% in groups 1 and 2, respectively. A significant increase was also noted in the survival rate from group 1 (63.3%: 105/166) to group 2 (75.5%: 259/343). This study has revealed that the steady advancement in antenatal diagnosis of congenital malformations, along with great efforts in terms of intensive care, has contributed to improved fetal
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