Monthly samples taken at two separate stations in the Queule River Estuary, between May 1980 and April 1981, were used to study annual fluctuations of the subtidal macroinfauna. In both stations, the macroinfauna showed a seasonal trend towards maximum densities and biomass in summer or autumn, with minimum densities during winter sampling, when salinities of bottom waters were the lowest. Annual variations of sedimentological characteristics did not show a direct relation with the seasonal trends presented by density and biomass.