In low to medium energy accelerators, betatron tune jumps and vertical orbit harmonic correction methods have been used to overcome the intrinsic and imperfection resonances. At high energy accelerators, snakes are needed to preserve polarization. We analyze the effects of snake resonances, snake imperfections overlapping resonances on the spin depolarization. We discuss also results of recent snake experiments at the IUCF Cooler Ring. The snake can overcome various kinds of spin depolarization resonances. These experiments pointed out further that partial snake can be used to cure the imperfection resonances in low to medium energy accelerators. We also examine various snake designs. A new generalized snake concept allows for two possible configurations. The compact configuration offers the advantages of shorter total snake length and smaller horizontal orbit displacement. The split snake configuration allows for dual functions of a snake and a 90° spin rotator at the mid‐section of the snake, which provides helicity state collisions. The requirements for obtaining high luminosity polarized protons at high energy colliders, such as RHIC and SSC, are reviewed.