Clinical, Radiographic, Histologic, and Histomorphometric Comparison of PepGen P-15 Particulate and PepGen P-15 Flow in Extraction Sockets: A Same-Mouth Case Study
作者:
Jack,
Hahn Michael,
Rohrer Andrew,
期刊:
Implant Dentistry
(OVID Available online 2003)
卷期:
Volume 12,
issue 2
页码: 170-174
ISSN:1056-6163
年代: 2003
出版商: OVID
关键词: enhanced bone regeneration;hydrogel;anorganic bone mineral
数据来源: OVID
摘要:
PurposeAlthough the efficacy of PepGen P-15 particulate has been conclusively demonstrated in two multicenter clinical studies, the effect of a new hydrogel formulation containing PepGen P-15 on bone repair has not been previously demonstrated.Materials and MethodsPepGen P-15 Flow contains PepGen P-15 particulate in a biocompatible hydrogel, which provides spacing between the particles. In this case study, bone repair of both PepGen P-15 particles and PepGen P-15 Flow was compared to natural bone in same-mouth extraction sockets.ResultsThe radiographic, histologic, and histomorphometric evaluations showed enhanced bone formation and faster particle resorption with PepGen P-15 Flow compared to the PepGen P-15 particulate.ConclusionThe accelerated bone formation by PepGen P-15 Flow may provide faster implant placement.
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