Redistribution of Intrarenal Blood Flow After Carotid Artery Occlusion in the Rat
作者:
Adelheid Schneider-Gilg,
Walter Ziegler,
Bruno Truniger,
期刊:
Nephron
(Karger Available online 1983)
卷期:
Volume 33,
issue 2
页码: 156-161
ISSN:1660-8151
年代: 1983
DOI:10.1159/000182931
出版商: S. Karger AG
关键词: Baroreceptor reflex;Prostaglandins;Renal blood flow;Carotid artery occlusion;Autoregulation;Renal nerves
数据来源: Karger
摘要:
As indicated by changes in microsphere distribution in the rat, acute bilateral carotid artery occlusion (CAO) was found to cause a small but significant increase in outer cortical flow fraction. When renal perfusion pressure was kept constant, no redistribution occurred upon CAO. In denervated kidneys the redistribution induced by CAO did not differ from that observed in contralateral control kidneys. Animals pretreated with prostaglandin inhibitors showed a significant redistribution in the ‘unprotected’ right kidney and a minor increase in outer cortical flow fraction in the normotensive kidney. It is concluded that: (1) the increase in outer cortical flow fraction induced by CAO in the rat is due to an increase in perfusion pressure, and (2) that this redistribution is independent of sympathetic vasoconstrictor stimuli, catecholamines and prostagland
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