CERTAIN PHYSICAL AND CHEMICAL PROPERTIES OF TWO MURINE LEUKEMIA VIRUSES
作者:
Eric R. Brown,
Peter Buinauskas,
S. O. Schwartz,
期刊:
Canadian Journal of Microbiology
(NRC Available online 1967)
卷期:
Volume 13,
issue 8
页码: 957-961
ISSN:0008-4166
年代: 1967
DOI:10.1139/m67-128
出版商: NRC Research Press
数据来源: NRC
摘要:
Various physicochemical characteristics and the biological activity of two murine lymphoma viruses (S-63 and GC), originally isolated in this laboratory and previously reported as sharing common antigenic properties with human and bovine lymphomas, are defined. These viruses are stable at temperature ranges from −70 °C to +4 °C and are inactivated after incubation at +56 °C for 30 min. They withstand lyophilization and are inactivated by treatment with ethanol, acetone, ethyl ether, formalin, and phenol. Both agents are of the ribonucleic acid, double-membraned viruses, similar to myxoviruses, and are approximately 100 mμ in size.
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