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Antiviral 1,3,4-Thiadiazoles

 

作者: Marion Tonew,  

 

期刊: Chemotherapy  （Karger Available online 1976）
卷期: Volume 22, issue 2  

页码: 114-120

 

ISSN:0009-3157

 

年代: 1976

 

DOI:10.1159/000221920

 

出版商: S. Karger AG

 

关键词: 1;3;4-Thiadiazoles;Incorporation of3H-uridine;Cellular RNA synthesis;Mengo-virus-induced RNA synthesis

 

数据来源: Karger

 

摘要:

Three antiviral 1,3,4-thiadiazoles caused, when incubated together with 3H-uridine, a reduction of the incorporation rate into acid-insoluble material of FL cells. Using the method of prelabelling cellular RNA synthesis was not remarkably influenced. However, the substances tested act as specific inhibitors of the virus-induced RNA synthesis.

 

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