Use of fibroblast cell culture for the study of wound healing drugs
作者:
M. ADOLPHE,
Y. POINTET,
X. RONOT,
J. WEPIERRE,
期刊:
International Journal of Cosmetic Science
(WILEY Available online 1984)
卷期:
Volume 6,
issue 1
页码: 55-58
ISSN:0142-5463
年代: 1984
DOI:10.1111/j.1467-2494.1984.tb00358.x
出版商: Blackwell Publishing Ltd
关键词: Wound healing drugs;cultured fibroblasts;proliferation
数据来源: WILEY
摘要:
SynopsisWound healing involves the activity of epithelial cells and fibroblasts. This process is particularly accompanied by an increase in the proliferative capacity of the fibroblasts and by the biosynthesis of constitutive proteins of connective tissue. To study the action of wound healing drugs on the growth of fibroblasts, they were cultured in a medium containing a suboptimal concentration of serum. Several growth factors (eye‐derived growth factor and fibroblast growth factor) were compared with various healing products for their effects on the growth curve. Some products slightly increased the proliferation of fibroblasts, in comparison with the optimal growth obtained with growth factors.Intérêt des fibroblastes en culture dans l'étude de produits cicatri
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