Importance of Renal Sympathetic Tone in the Development of DOCA‐Salt Hypertension in the Rat
作者:
RICHARD KATHOLI,
ALLEN NAFTILAN,
SUZANNE OPARIL,
期刊:
Hypertension
(OVID Available online 1980)
卷期:
Volume 2,
issue 3
页码: 266-273
ISSN:0194-911X
年代: 1980
出版商: OVID
关键词: KEYWORDS;DOCA-salt;sodium;renal denervation;sympathetic nervous system;Sprague-Dawley rat;hypertension
数据来源: OVID
摘要:
SUMMARY In many experimental models, acute increases in sympathetic nerrous system activity produce disproportionately greater vasoconstriction in the renal vascular bed than occurs in most other vascular beds. Since increased sympathetic nervous system activity has been implicated in the patbogenesis of DOCA-salt hypertension in the rat, we hypothesized that an attenuation of renal sympathetic tone would delay the development of this form of hypertension.
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