Diagnosis and staging of chronic pancreatitis is based on patient history, clinical findings, and various diagnostic tools. Usually, a combination of both, investigations of pancreatic function and pancreatic structure are necessary for an accurate diagnosis. This paper gives an overview of the most widely used function tests (PABA Test, Pancreolauryl Test, Secretin Test) and the various imaging techniques (plain X-ray, ultrasound, CT scan, ERCP). Currently, ERCP is the most sensitive method for analyzing the structure of the pancreatic duct system and it provides valuable information for the selection of patients who may benefit from surgical or endoscopic therapy.