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Photometric Flow Injection Determination of Psychotropic Drugs: Brotizolam and Midazolam

 

作者: B. Gallo,   R.M. Alonso,   F. Vicente,   J-C. Vire,   G.J. Patriarche,  

 

期刊: Analytical Letters  （Taylor Available online 1988）
卷期: Volume 21, issue 7  

页码: 1211-1220

 

ISSN:0003-2719

 

年代: 1988

 

DOI:10.1080/00032718808055508

 

出版商: Taylor & Francis Group

 

关键词: Flow injection analysis;photometric detection;Brotizolam;Midazolam;pharmaceuticals

 

数据来源: Taylor

 

摘要:

Brotizolam and Midazolam, psychotropic drugs belonging to thienotriazolodiazepine and imidazobenzodiazepine families, have been determined by flow injection analysis with photometric detection. At pH 7, signals showed to be rectilinear from 1.27 × 10−6M to 1.07 × 10−4M for brotizolam and from 1.53 × 10−6M to 1.07 × 10−4M for midazolam. Methods developed were applied to the determination of both drugs in their formulations (Lendormin and Dormicum).

 

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