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Mesangial Proliferative Glomerulonephritis with IgM Deposits

 

作者: Przemyslaw Hirszel,   Harold T. Yamase,   William R. Carney,   Malcolm A. Galen,   Charles W. Graeber,   Kent J. Johnson,   Thomas L. Kennedy,   Robert A. Lapkin,   Robert H. McLean,   Elliott Rosenworcel,   Dale A. Rowett,  

 

期刊: Nephron  （Karger Available online 1984）
卷期: Volume 38, issue 2  

页码: 100-108

 

ISSN:1660-8151

 

年代: 1984

 

DOI:10.1159/000183289

 

出版商: S. Karger AG

 

关键词: Mesangial proliferative glomerulonephritis;Minimal change disease;Focal segmental glomerulosclerosis;IgM deposits

 

数据来源: Karger

 

摘要:

To determine the natural history of mesangial proliferative glomerulonephritis (MesPGN) with IgM deposits and its relationship to minimal change disease (MC) and focal segmental glomerulosclerosis (FGS), we studied the clinical characteristics and outcome in 20 patients with MesPGN, 8 with MC, and 10 with FGS. IgM deposits were present in glomeruli of all MesPGN patients. Progression to FGS was documented in 2 patients with MesPGN, 1 of whom developed renal failure. Transition from MC to MesPGN occurred in 1 patient. 2 MC patients developed FGS, with decline in renal function in 1 of them. These data suggest the possibility of histologic transition from MC to FGS directly or through the stage of MesPGN.

 

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