Plasma Protein Binding and Therapeutic Drug Monitoring
作者:
Malcolm,
期刊:
Therapeutic Drug Monitoring
(OVID Available online 1980)
卷期:
Volume 2,
issue 1
页码: 29-38
ISSN:0163-4356
年代: 1980
出版商: OVID
关键词: Plasma protein binding;Measurement;Representation;Pharmacokinetics;Therapeutic monitoring
数据来源: OVID
摘要:
Aspects of measurement of plasma protein-binding of drugs and the representation and interpretation of such data, together with the effect of altered binding on pharmacokinetics and the impact on therapeutic plasma drug concentration monitoring, are reviewed. In most instances, altered binding affects interpretation of plasma concentration data rather than causes a need for a change in the usual dosage regimen.
点击下载:
PDF
(576KB)
返 回