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Development and viability of offspring of male mice treated with chlorinated phenoxy ac...
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Development and viability of offspring of male mice treated with chlorinated phenoxy acids and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin
作者:
JamesC. Lamb,
JohnA. Moore,
ThomasA. Marks,
JosephK. Haseman,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1981)
卷期:
Volume 8,
issue 5-6
页码: 835-844
ISSN:0098-4108
年代: 1981
DOI:10.1080/15287398109530119
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Male C57BL/6 mice were given feed containing various concentrations of 2,4‐dichlorophenoxyacetic acid (2,4‐D), 2,4,5‐trichlorophenoxyacetic acid (2,4,5‐T) and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) such that their diets contained daily doses of approximately 40 mg/kg 2,4‐D, 40 mg/kg 2,4,5‐T, and 2.4 μg/kg TCDD (group II); 40 mg/kg 2,4‐D, 40 mg/kg 2,4,5‐T, and 0.16 μg/kg TCDD (group III); or 20 mg/kg 2,4‐D, 20 mg/kg 2,4,5‐T, and 1.2 μg/kg TCDD (group IV). Controls (group I) were given a diet with only the corn oil vehicle added to the feed.
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