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Development and viability of offspring of male mice treated with chlorinated phenoxy acids and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin

 

作者: JamesC. Lamb,   JohnA. Moore,   ThomasA. Marks,   JosephK. Haseman,  

 

期刊: Journal of Toxicology and Environmental Health  (Taylor Available online 1981)
卷期: Volume 8, issue 5-6  

页码: 835-844

 

ISSN:0098-4108

 

年代: 1981

 

DOI:10.1080/15287398109530119

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Male C57BL/6 mice were given feed containing various concentrations of 2,4‐dichlorophenoxyacetic acid (2,4‐D), 2,4,5‐trichlorophenoxyacetic acid (2,4,5‐T) and 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) such that their diets contained daily doses of approximately 40 mg/kg 2,4‐D, 40 mg/kg 2,4,5‐T, and 2.4 μg/kg TCDD (group II); 40 mg/kg 2,4‐D, 40 mg/kg 2,4,5‐T, and 0.16 μg/kg TCDD (group III); or 20 mg/kg 2,4‐D, 20 mg/kg 2,4,5‐T, and 1.2 μg/kg TCDD (group IV). Controls (group I) were given a diet with only the corn oil vehicle added to the feed.

 

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