Evidence that the chick lens cytoskeletal protein CP 49 belongs to the family of intermediate filament proteins
作者:
OriiHidefumi,
AgataKiyokazu,
SawadaKaichiro,
EguchiGoro,
MaiselHarry,
期刊:
Current Eye Research
(Taylor Available online 1993)
卷期:
Volume 12,
issue 6
页码: 583-588
ISSN:0271-3683
年代: 1993
DOI:10.3109/02713689309001836
出版商: Taylor&Francis
数据来源: Taylor
摘要:
A partial cDNA sequence for chick lens beaded-filament protein CP 49 showed the greatest similarity to the sequence of acidic cytokeratins, especially human cytokeratin 18. The predicted amino acid sequence of chick CP 49 corresponded to the entire coil 1a region of the rod domain of human cytokeratin 18, spacer 1, coil 1b, spacer 2 and about half of coil 2. For this sequence of 242 amino acids, there was an overall 38% identity and 76.8% similarity between the chick CP 49 and human cytokeratin 18. This is further evidence that CP 49 belongs to the family of intermediate filament proteins.
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