Recent Advances in the Treatment of Breast Cancer
作者:
LANE ZIEGLER,
AMAN BUZDAR,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1991)
卷期:
Volume 301,
issue 5
页码: 337-352
ISSN:0002-9629
年代: 1991
出版商: OVID
关键词: Breast cancer;Adjuvant treatment;Endocrine treatment;Chemotherapy;Node-negative disease.
数据来源: OVID
摘要:
Multidisciplinary efforts have defined a number of prognostic factors and newer strategies to improve the outcome of patients with breast cancer. Conservative surgery has led to improved functional and cosmetic results. The development of a number of effective adjuvant regimens has led to improved survival. In patients with stage I disease, several biological characteristics of tumor have been identified that are associated with increased risk of relapse. A multimodality approach to patients with locally advanced disease and inflammatory cancer has resulted in improved survival. A number of hormonal and cytotoxic drug contaminations can palliate metastatic disease, with a small fraction of patients remaining in extended remission. Dose-intensive programs may lead to further improvements in survival of selected patients with this disease.
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