Fluorescence in situ mapping of the human nuclear NAD+ADP-ribosyltransferase gene (ADPRT) and two secondary sites to human chromosomal bands 1q42, 13q34, and 14q24
作者:
M. Baumgartner,
R. Schneider,
B. Auer,
H. Herzog,
M. Schweiger,
M. Hirsch-Kauffmann,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1992)
卷期:
Volume 61,
issue 3
页码: 172-174
ISSN:1424-8581
年代: 1992
DOI:10.1159/000133400
出版商: S. Karger AG
数据来源: Karger
摘要:
A 3.5-kb cDNA probe containing the 23 exons from the coding sequence of human nuclear NAD+ ADP-ribosyltransferase (poly [ADP-ribose] polymerase [ADPRT], E.C.2.4.2.30) was used to map the gene and two additional sites by nonisotopic in situ chromosomal hybridization. The previous localization of the structural gene on 1q42 was confirmed. Two other hybridization peaks on 13q34 and 14q24 suggested the presence of ADPRT pseudogenes.
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