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Lack of effect of liver disease on the pharmacokinetics of acebutolol and diacetolol: A single dose study

 

作者: R. Zaman,   D. B. Jack,   M. R. Wilkins,   M. J. Kendall,  

 

期刊: Biopharmaceutics&Drug Disposition  （WILEY Available online 1985）
卷期: Volume 6, issue 2  

页码: 131-137

 

ISSN:0142-2782

 

年代: 1985

 

DOI:10.1002/bdd.2510060204

 

出版商: John Wiley&Sons, Ltd.

 

关键词: Acebutolol;Diacetolol;Pharmacokinetics;Liver disease

 

数据来源: WILEY

 

摘要:

AbstractThe pharmacokinetics of acebutolol and its major metabolite, diacetolol, following a single 400 mg oral dose, were investigated in patients with liver disease. No significant differences were found in any of the parameters measured.

 

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