Effect of Glycyrrhizin on Pain and HLA-DR Antigen Expression on CD8-Positive Cells in Peripheral Blood of Herpes zoster Patients in Comparison with Other Antiviral Agents
作者:
Yosuke Aikawa,
Takashi Yoshiike,
Hideoki Ogawa,
期刊:
Skin Pharmacology and Physiology
(Karger Available online 1990)
卷期:
Volume 3,
issue 4
页码: 268-271
ISSN:1660-5527
年代: 1990
DOI:10.1159/000210879
出版商: S. Karger AG
数据来源: Karger
摘要:
Glycyrrhizin (GL) is a saponin widely used as an anti-inflammatory agent. Pain intensity and HLA-DR antigen expression on CD8+ cells were assessed during and after treatment with GL. Other agents such as acyclovir,γ-globulin and interferon β were also administered for comparison. Pain resolved most rapidly among those treated with acyclovir followed by those treated with GL. Pain resolution correlated with the regression of HLA-DR+ in CD8+ subpopulations in peripheral blood. GL is suggested to be an alternative or additive antiviral agent to herpes zoste
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