Transient expression of SorCS in developing telencephalic and mesencephalic structures of the mouse
作者:
Guido Hermey,
H. Schaller,
Irm Hermans-Borgmeyer,
期刊:
NeuroReport
(OVID Available online 2001)
卷期:
Volume 12,
issue 1
页码: 29-32
ISSN:0959-4965
年代: 2001
出版商: OVID
关键词: Dopaminergic nuclei;Nervous system development;VPS10 domain receptor
数据来源: OVID
摘要:
Here we describe the expression of a third member of the VPS10 domain containing receptor family, SorCS, during mouse embryonal and early postnatal nervous system development. SorCS is expressed in a unique transient and dynamic pattern in regions where cells proliferate, as well as in areas where already differentiated cells reside, including the cerebral cortex, the ventral tegmental area, and the globus pallidus. Transcripts were absent from fiber tracts hinting at a neuronal expression. The only exception was hybridization signals on the developing optic nerve correlating with the appearance of astrocytes migrating into the retina.
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