I was extremely delighted to be invited to write a review of PhacoTmesis. However, there is not enough existing literature to review other than a few short articles authored by myself and a few short statements made by some investigators commenting on their short one-time trial of PhacoTmesis. The reason for this is that it has taken Chiron (Clairmont, CA) and myself more than 5 years to develop and evolve the concept and the machine to the level at which it can be used clinically with safety and efficiency prior to making it available to other ophthalmologists to explore its capabilities.