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The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3→q22.1 and 16q22→q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci

 

作者: M. Parmentier,   E. Passage,   G. Vassart,   M.-G. Mattei,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1991）
卷期: Volume 57, issue 1  

页码: 41-43

 

ISSN:1424-8581

 

年代: 1991

 

DOI:10.1159/000133111

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

The genes encoding calbindin D28k (CALB1) and calretinin (CALB2), two closely related calcium-binding proteins, were mapped by in situ hybridization to the 8q21.3→ q22.1 and 16q22→q23 regions of the human genome, respectively. These localizations match the chromosomal regions where the carbonic anhydrase isozyme gene cluster (CA1 CA2, CA3) and the related gene CA7 have been described, respectively. This suggests a common duplication·the calbindin/calretinin and the carbonic anhydrase ancestral g

 

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