WETTABILITY OF DRUG LOADED POLYMER MATRICES
作者:
Véronique Rosilio,
Maria de Lourdes Costa,
Adam Baszkin,
期刊:
Journal of Dispersion Science and Technology
(Taylor Available online 1998)
卷期:
Volume 19,
issue 6-7
页码: 821-841
ISSN:0193-2691
年代: 1998
DOI:10.1080/01932699808913217
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Drug release is to a large extent influenced by penetration of a dissolution liquid into a polymer matrix. If an aqueous medium does not wet a matrix, its penetration into the polymer bulk and the resulting drug extraction would be considerably hindered. It is therefore of extreme importance to study not only the physical state of drug loaded matrices but also their wettability and their penetration by an aqueous medium.
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