SUMMARYA variety of yeast-like fungi representing the generaCandida, Cryptococcus, Rhodotorula, Torulopsis, andTrichosporonwas inhibited in vitro in the presence of an aqueous extract of garlic. Fungi associated with vaginitis were inhibited and killed by an aqueous garlic extract diluted to1: 1024 when incubated at 37 C. The antimycotic activity of the garlic preparation appeared greater at 37 C than at 30 C. The aqueous garlic extract maintained its fungistatic properties at 4,–10,–60 C for the test period of 30 da, but decreased in fungicidal ability within one wk at the same storage temperatures. Twenty-two isolates ofC. albicansisolated from active vaginitis cases were all inhibited by the garlic extract.