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Functional Significance of Mild Cognitive Impairment in Elderly Patients Without a Dementia Diagnosis

 

作者: Steven Albert,   K. Michaels,   M. Padilla,   G. Pelton,   K. Bell,   K. Marder,   Y. Stern,   D. Devanand,  

 

期刊: American Journal of Geriatric Psychiatry  (OVID Available online 1999)
卷期: Volume 7, issue 3  

页码: 213-220

 

ISSN:1064-7481

 

年代: 1999

 

出版商: OVID

 

关键词: Alzheimer's Disease;Cognition;Functional Impairment

 

数据来源: OVID

 

摘要:

The authors investigated differences in functional ability among three groups of subjects who were not diagnosed with dementia: normal control (NC) subjects (n=35); Clinical Dementia Rating Scale (CDRS) score of 0 (minimal impairment; n=26); and CDRS 0. 5 (questionable dementia; n=42). CDRS 0 and 0. 5 patients reported significantly poorer functioning than NCs in household and other activities, but CDRS 0 and CDRS 0. 5 groups did not differ in self-reported functioning. It is likely that CDRS 0. 5 patients overestimated their functional abilities. Correlations between self- and informant reports of functional status were significantly lower in the CDRS 0. 5 group than in the CDRS 0 group, an important finding for clinical management because patients with questionable dementia may actually be more impaired than they admit. Informants' reports or standardized performance-based assessment should be considered in the clinical evaluation of such patients.

 

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