Statin therapy produces modest and reversible reductions in BP, according to studies presented at the Annual Scientific Sessions of the American Heart Association (AHA) [New Orleans, US; November 2004]. Reductions in diastolic and systolic BP were observed with pravastatin and simvastatin in the UCSD Statin Study. An analysis of data from the ASCOT-LLA study found that atorvastatin treatment was associated with a small but significant reduction in BP, compared with placebo.