Non-Typhoid Salmonella Infections after Renal Transplantation
作者:
M.R. Berk,
A.M. Meyers,
W. Cassal,
J.R. Botha,
J.A. Myburgh,
期刊:
Nephron
(Karger Available online 1984)
卷期:
Volume 37,
issue 3
页码: 186-189
ISSN:1660-8151
年代: 1984
DOI:10.1159/000183241
出版商: S. Karger AG
关键词: Non-typhoid salmonella infections;Renal transplantation;Recurrence
数据来源: Karger
摘要:
A retrospective study of 410 renal transplant recipients showed that 1.96% (8/410) of patients had developed severe non-typhoid salmonella infections. The clinical features seen were fever, leucopenia, pneumonia, diarrhoea, abscesses, pyelonephritis, venous thrombosis and pleural effusion. Neither uraemia nor repeated high doses of steroids seemed to be major precipitating events. All isolates were strains of Salmonella entiritidis. All 8 patients were cured and none became permanent carriers. Salmonella infections cause severe, life-threatening infections in renal transplant patients and require vigorous treatment often with a long-term low-dose regimen. Patients seemed to respond best to chloramphenicol, but ampicillin and co-trimoxazole were useful in some. Bilateral nephrectomy should be performed before the transplantation if the organism is grown from the urine.
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