Cytomegalovirus Esophagitis as a Treatable Complication of Systemic Sclerosis
作者:
Ma Contreras,
Clara Salas,
José Andreu,
Juan Mulero,
期刊:
JCR: Journal of Clinical Rheumatology
(OVID Available online 2001)
卷期:
Volume 7,
issue 6
页码: 384-387
ISSN:1076-1608
年代: 2001
出版商: OVID
关键词: Cytomegalovirus esophagitis;Cytomegalovirus infection;Cytomegalovirus disease;Systemic sclerosis;Limited scleroderma
数据来源: OVID
摘要:
We report the case of a 51-year-old woman with a connective tissue disease of 8 years duration. She had been taking corticosteroids at a dose of 1 mg/kg/day and azathioprine at a dose of 3 mg/kg/day for 1 month. Given the clinical suspicion of systemic sclerosis (limited form of scleroderma), she was studied according to a protocol including endoscopy to assess the degree to which the underlying disease had affected the gastrointestinal tract. Endoscopy revealed a asymptomatic severe esophagitis and a subsequent biopsy disclosed the presence of cytomegalovirus.Cytomegalovirus pneumoniawas also detected. Both processes were successfully managed with intravenous ganciclovir (5 mg/kg/12 hr) for 21 days.This report is a case of cytomegalovirus involving the esophagus in association with systemic sclerosis in a patient immunosuppressed because of drugs that she had been taking. This complication can be asymptomatic and is amenable to treatment.
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