Allograft bone tissue is frequently used in orthopaedic reconstructive surgery. At many major medical centers, this procedure is as routine as the implantation of manmade metallic prosthetics. The harvesting, preparation, and delivery of bone used for transplantation is a complex and intricate process coupled with varying practices among different bone banks. This article provides the reader with information on current standards and practices in bone banking and transplantation. This will help the perioperative orthopaedic nurse deliver safe patient care during procedures using cadaveric bone and tissue.