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Chordoma and Chondrosarcoma of the Cranial Base: An 8‐Year Experience

 

作者: Chandra Sen,   Laligam Sekhar,   Victor Schramm,   Ivo Janecka,  

 

期刊: Neurosurgery  (OVID Available online 1989)
卷期: Volume 25, issue 6  

页码: 931-941

 

ISSN:0148-396X

 

年代: 1989

 

出版商: OVID

 

关键词: Chondrosarcoma;Chordoma;Proton beam radiation;Skull base tumor

 

数据来源: OVID

 

摘要:

&NA;Between 1980 and 1988, 8 patients with chordomas and 9 with low‐grade chondrosarcomas involving the cranial base were treated. All the patients were investigated preoperatively and postoperatively with computed tomographic or magnetic resonance imaging scans, according to a standard protocol. The tumors and the involved bony structures were surgically removed in one or more operations using different operative approaches. Ten patients underwent postoperative radiation therapy, either at our institution or prior to their referral to us.Total removalwas defined as the absence of identifiable tumor on magnetic resonance imaging or computed tomographic obtained 3 months postoperatively, and was accomplished in 9 patients. The ability to achieve total removal was greatly increased in patients with tumors that had not previously been operated on. We believe that these tumors must be treated by aggressive surgical resection when initially diagnosed, and this can be accomplished with low morbidity. The follow‐up period in our patients was too short to allow us to determine whether such total removals can result in a cure or in long‐term control of these formidable tumors. (Neurosurgery25:931‐941, 1989)

 

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