Comparative Sequence Analyses of Epstein-Barr Virus Nuclear Antigen-2 and -3B Genes of a Fresh Epstein-Barr Virus-2 Isolate
作者:
Naoki Inoue,
Hídeaki Kikuta,
Kazuo Yanagi,
期刊:
Intervirology
(Karger Available online 1992)
卷期:
Volume 33,
issue 4
页码: 180-186
ISSN:0300-5526
年代: 1992
DOI:10.1159/000150249
出版商: S. Karger AG
关键词: Epstein-Barr virus-2 isolate;Epstein-Barr virus nuclear antigens;Nucleotide sequence
数据来源: Karger
摘要:
The nucleotide sequence of Epstein-Barr virus (EBV) nuclear antigen (EBNA)-2 and EBNA-3B regions of an EBV-2 isolate in Japan was analyzed. The deduced amino acid sequences of EBNA-2 and EBNA-3B of the isolate and a prototype EBV-2 strain AG876 were identical, but the number of the repeated sequence in EBNA-3B was variable as that of IR-3 in EBNA-1. The remarkably well-conserved sequence seems to suggest that the structure of the EBNA-2 and EBNA-3B genes of EBV-2 is crucial for their function in virus replication.
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