首页   按字顺浏览 期刊浏览 卷期浏览 Study of Alpha-Thalassemia in Northeastern Thailand at the DNA Level
Study of Alpha-Thalassemia in Northeastern Thailand at the DNA Level

 

作者: J. Hundrieser,   Marion Laig,   P. Yongvanit,   P. Sriboonlue,   T. Sanguansermsri,   W. Kühnau,   M. Pape,   G. Flatz,  

 

期刊: Human Heredity  （Karger Available online 1990）
卷期: Volume 40, issue 2  

页码: 85-88

 

ISSN:0001-5652

 

年代: 1990

 

DOI:10.1159/000153911

 

出版商: S. Karger AG

 

关键词: α-Thalassemia;Hemoglobin Constant Spring;Population study;Thailand

 

数据来源: Karger

 

摘要:

The frequency of α-thalassemias in a general population sample from northeastern Thailand and in an Austroasiatic group with high frequencies of hemoglobin E and β-thalassemia, the So, was estimated using DNA techniques. Among 64 healthy adult subjects from the Khonkaen and Ubol areas, the following haplotype frequencies were determined: αα, 0.742; -α3.7 (subtype I), 0.148; -α4.2, 0.016; -αdel, 0.008; Constant springy 0.055. __sea, 0.023 and ααα (triplicated α-globin gene), 0.008. In the So group, the combined frequency of α-thalassemia chromosome

 

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