Regulatory Effect of Cell Density on the Platelet-aggregating Activity of Human Melanoma Cell Line
作者:
KatagiriY.,
HayashiY.,
BabaI.,
YamazakiH.,
TanoueK.,
期刊:
Platelets
(Taylor Available online 1995)
卷期:
Volume 6,
issue 4
页码: 204-208
ISSN:0953-7104
年代: 1995
DOI:10.3109/09537109509078456
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Human melanoma cell Line, HMV-I, has been shown to induce platelet aggregation without thrombin generation. The platelet-aggregating activity of HMV-I cells increased with increasing culture periods of the cells. However, data indicate that the platelet-aggregating activity of HMV-I cells is dependent upon the cell density of the culture and does not result from the culture periods- nor cell cycle-dependent regulation. It is suggested that this effect of cell density is referred to as density-induced upregulation of platelet-aggregating activity.
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