Prospective study of suspected associations between certain drugs administered during early pregnancy and congenital malformations
作者:
J. Michaelis,
H. Michaelis,
E. Glück,
S. Koller,
期刊:
Teratology
(WILEY Available online 1983)
卷期:
Volume 27,
issue 1
页码: 57-64
ISSN:0040-3709
年代: 1983
DOI:10.1002/tera.1420270109
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractFrom 1964 to 1976, a cohort study was performed in West Germany to study the possible influence of various factors on pregnancy and child development. Results of the evaluation of 13,643 pregnancies are given with respect to possible teratogenetic effects of antiemetic drugs and sex hormones administered in early pregnancy. There was no evidence of an increased risk of major malformations following the intake of certain antiemetic drugs and progesterone. Also, the use of a hormonal pregnancy test was not significantly associated with an increase of major malformations.
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