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Statistical Mixture Design Applied to RP-HPTLC Chromatographic Separations of Amino Acid Hydroxamates

 

作者: FrederickH. Walters,   Hongchun Qiu,  

 

期刊: Analytical Letters  （Taylor Available online 1993）
卷期: Volume 26, issue 8  

页码: 1787-1797

 

ISSN:0003-2719

 

年代: 1993

 

DOI:10.1080/00032719308021496

 

出版商: Taylor & Francis Group

 

关键词: Mixture design;amino acid hydroxamates;reversed phase high performance thin layer chromatography

 

数据来源: Taylor

 

摘要:

Mixture Design and a Chromatographic Response Function were used to study the effect of different organic solvents as modifiers on the Reversed Phase (C-18) High Performance Thin Layer Chromatographic separation of three amino acid hydroxamates (Arginine hydroxamate, Threonine hydroxamate, and Histidine hydroxamate). Both 3 solvent (methanol, acetonitrile and tetrahydrofuran) and 4 solvent (methanol, acetonitrite, tetrahydrofuran and acetone) systems were studied.

 

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