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A Comparison of Antisera against Thymocytes, Lymphocytes and Subcellular Fractions in Rats

 

作者: H.J. Halbfass,   D. Paravicini,   H. Schäfer,   W. Michaelis,   I. Staib,  

 

期刊: European Surgical Research  （Karger Available online 1971）
卷期: Volume 3, issue 2  

页码: 122-129

 

ISSN:0014-312X

 

年代: 1971

 

DOI:10.1159/000127558

 

出版商: S. Karger AG

 

关键词: Antilymphocyte serum;Subcellular fractions;Lymphocytotoxicity;Skin transplantation

 

数据来源: Karger

 

摘要:

Comparative studies were done in inbred rats with antisera against lymphocytes, thymocytes and subcellular fractions using two immunization methods.The cellhomogenate was separated into 4 fractions. Antisera against mitochondrial-granular fractions and total cells yielded strongest immunosuppression and highest lymphocytotoxic titers. Toxicity was higher when antisera were produced with total cells than with subcellular fractions and when adjuvant was used.

 

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