A number of S. E. Asian taxa of Acanthaceae are here recognized as belonging to the prevailingly African genusIsoglossa. The reasons for doing so are briefly outlined. The synonymy, as regards S. E. Asian Isoglossa, is worked out, generic as well as specific. The following new combinations are formally made:Isoglossa clemensorum(R. Benoist) comb. nov.,I. collina(T. Anderson) comb. nov.,I. geoffrayi(R. Benoist) comb. nov.,I. glabra(Hand.‐Mazz.) comb. nov.,I. inermis(R. Benoist) comb. nov., andI. subcordafa(C. B. Clarke) comb. nov. The distribution is outlined and mapped.I. dichotomais shown to occur in Africa, whereI. lactea, andI. strigosulaare sunk into its synonym