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Nephrotoxicity following Single Dose Mithramycin Therapy

 

作者: Robert G. Benedetti,   John Heilman, III,   Patricia A. Gabow,  

 

期刊: American Journal of Nephrology  （Karger Available online 1983）
卷期: Volume 3, issue 5  

页码: 277-278

 

ISSN:0250-8095

 

年代: 1983

 

DOI:10.1159/000166729

 

出版商: S. Karger AG

 

关键词: Single dose mithramycin;Nephrotoxicity;Acute renal failure;Hypercalcemia

 

数据来源: Karger

 

摘要:

Mithramycin given as a single dose for the treatment of hypercalcemia has not been reported to cause renal dysfunction. A case is presented of nephrotoxicity following a single 25 μg/kg dose in a patient with underlying squamous cell carcinoma, obstructive uropathy, and hypercalcemia. Underlying renal impairment may magnify the nephrotoxicity of mithramycin

 

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