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Effect on Rat Caries of Endogenous and Exogenous Hydrogen Peroxide

 

作者: H.R. Mühlemann,   R. Schmid,   A.R. Firestone,  

 

期刊: Caries Research  （Karger Available online 1981）
卷期: Volume 15, issue 1  

页码: 46-53

 

ISSN:0008-6568

 

年代: 1981

 

DOI:10.1159/000260499

 

出版商: S. Karger AG

 

关键词: Amyloglucosidase;Caries;Chlorhexidine;Fluoride dentifrices;Glucose oxidase;Hydrogen peroxide;Mutanase

 

数据来源: Karger

 

摘要:

A toothpaste containing sodium fluoride and enzymes activating the anti-glycolytic lactoperoxidase-thiocyanate system was without inhibitory effects in 3 independent rat caries studies on formation of plaque, and smooth surface and fissure caries lesions when compared with a corresponding topical fluoride treatment. In contrast, topical hydrogen peroxide, mutanases, chlorhexidine and various fluoride dentifrices inhibited caries incidence significantly.

 

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