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Binding of Salivary Aggregating Factors forStreptococcus mutansby Concanavalin A and Fucose-Binding Protein

 

作者: Dale B. Mirth,   Carol J. Miller,   Albert Kingman,   William H. Bowen,  

 

期刊: Caries Research  （Karger Available online 1981）
卷期: Volume 15, issue 1  

页码: 1-8

 

ISSN:0008-6568

 

年代: 1981

 

DOI:10.1159/000260493

 

出版商: S. Karger AG

 

关键词: Concanavalin A;Fucose-binding protein;Lectins;Salivary aggregating factors;Streptococcus mutans

 

数据来源: Karger

 

摘要:

Concanavalin A and fucose-binding protein, lectins with a high specificity for binding to D-mannose or D-glucose and L-fucose, respectively, have been found to reversibly bind and inactivate the factor or factors in saliva that are responsible for inducing the aggregation of Streptococcus mutans. The sugars for which the lectins are specific can block and reverse the binding, suggesting that the lectins are binding to specific sugar residues in the carbohydrate portion of the aggregating factor molecule.

 

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