Observation of a reversible, medication‐induced change in pitch perception
作者:
Vladimir Chaloupka,
Stephen Mitchell,
Richard Muirhead,
期刊:
The Journal of the Acoustical Society of America
(AIP Available online 1994)
卷期:
Volume 96,
issue 1
页码: 145-149
ISSN:0001-4966
年代: 1994
DOI:10.1121/1.411437
出版商: Acoustical Society of America
关键词: TONES;HEARING;STIMULI;FREQUENCY DEPENDENCE;TIME DEPENDENCE;DRUGS;PHARMACOLOGY
数据来源: AIP
摘要:
This paper reports a study of an absolute pitch possessor who, upon administration of the psychoactive drug Tegratol (carbamazepine), experienced a significant change in her pitch perception. The subject’s performance both in producing, as well as in identifying, random‐frequency tones was measured, covering the period of administration of the drug, as well as control periods before and after. The main effect of the drug was a downward shift of the perceived pitch as compared to the two control periods. The magnitude of the shift was observed to increase with increasing fundamental frequency of the stimulus; the average shift was about one semitone. Detailed results on the frequency dependence and time dependence of the pitch shifts are presented. This may be the first documented report of a significant, reversible change of pitch perception caused by a medication.
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